منابع مشابه
Bioinformatics and Drug Discovery
Bioinformatic analysis can not only accelerate drug target identification and drug candidate screening and refinement, but also facilitate characterization of side effects and predict drug resistance. High-throughput data such as genomic, epigenetic, genome architecture, cistromic, transcriptomic, proteomic, and ribosome profiling data have all made significant contribution to mechanismbased dr...
متن کاملUsing bioinformatics in gene and drug discovery.
Bioinformatics has, out of necessity, become a key aspect of drug discovery in the genomic revolution, contributing to both target discovery and target validation. The author describes the role that bioinformatics has played and will continue to play in response to the waves of genome-wide data sources that have become available to the industry, including expressed sequence tags, microbial geno...
متن کاملIntegrating Bioinformatics, Medical Sciences and Drug Discovery
Walter Gilbert, a renowned scientist, described this shift in biology as follows: "The new paradigm, now emerging, is that all of the “genes” will be known (in the sense of being resident in databases available electronically), and that the starting point of a biological investigation will be theoretical. An individual scientist will begin with a theoretical conjecture only then turning to expe...
متن کاملEthnobotany, Ethnopharmacology and Drug Discovery
This manuscript is a review of a number of ethnobotany and ethnopharmacology texts and papers in order to arrive at current understanding and scope of ethnobotany and ethnopharmacology. It includes either a brief definition of both fields and presenting some examples on them. Also it has a glimpse on the geographical coverage of research works throughout the world, important issue of prope...
متن کاملBioinformatics in Drug Discovery a Review
ISSN: 2394-9759| © 2016 Bonfring Abstract--The drug discovery process was beginning in 19 century by John Langley in 1905 when he proposed the theory of respective substances. Drug discovery is the step-bystep process by which new candidate drugs are discovered. Bioinformatics deals with the exponential growth and the development in primary and secondary databases like nucleic acid sequences, p...
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ژورنال
عنوان ژورنال: Current Topics in Medicinal Chemistry
سال: 2017
ISSN: 1568-0266
DOI: 10.2174/1568026617666161116143440